It is estimated that some 50 million Americans will choose to diet this year. Sadly, 95% of these individuals will fail to keep weight off long-term. With only 5% of annual dieters succeeding to find a solution to their weight loss needs, it is imperative that support be available for persons wishing to make changes to their current lifestyle.

Lipitrex has been designed for such a purpose and is the most logical choice for fat loss. This unique formulation offers not one, but four beneficial actions for supporting your weight loss goals:

1. Appetite Control
   
   
2. Helps to Minimize the Storage of Fat
   
   
3. Increases Metabolic Rate
   
   
4. Enhances Energy Levels

The term overweight is used to denote a human, or other mammal, that has more body fat than is required for normal physiological processes. Today, being overweight is extremely common. In fact some 64% of Americans are classified as being overweight. This number is expected to steadily increase as exercise and dietary practices are ignored more with each passing year.

The United States National Institutes of Health, as well as the World Health Organization, use the Body Mass Index (BMI) as a means to determine if one is overweight. However, it should be noted that BMI does not account for differing amounts of muscle mass, genetic factors, or other individuals variations. A BMI between 25-30 is considered overweight, but not obese. Being overweight has many health implications, but is less influential then obesity.

Lipitrex has been formulated to assist in your current and future weight loss goals. With its unique formulation of potent botanical extracts, Lipitrex effectively diminishes appetite and increases Your body's natural fat-burning processes.

The cAMP factor:

Progressive Health's recently updated Lipitrex formulation includes the Indian plant, Coleus Forskohlii. Coleus forskohlii roots, the only known plant source of forskolin, is a natural compound that has been shown to increase lean body mass and helps optimize body composition through cAMP activation. This diterpene (coleus) directly activates adenylate cyclase and raises the levels of the important cell regulating compound, cyclic AMP (cAMP), in a variety of tissues. Normally, cAMP is formed when a stimulatory hormone, like epinephrine, binds to a receptor site on the cell membrane and stimulates the activation of adenylate cyclase. Adenylate cyclase is an enzyme that is incorporated into all cellular membranes.

Forskolii appears to aid the body in bypassing its need for direct hormonal activation of adenylate cyclase. As a result of this direct activation of adenylate cyclase, intracellular cAMP levels rise. Raised intracellular cAMP levels have shown to decrease fat deposition and promote other significant physiological and biochemical effects, including:

• Increased insulin secretion
• Increased thyroid function
• Inhibition of mast cell degranulation and histamine release
• Increased force of contraction of heart muscle
• Relaxation of the arteries and other smooth muscles
• Inhibition of platelet activation

However, the greatest benefit witnesses by increases of intracellular cAMP by means of coleus forskolin supplementation still lies within Fat Loss.

A study published in the December 2005 Journal of the International Society of Sports Nutrition entitled "Effects of Coleus forskohlii extract supplementation on body composition and markers of health in sedentary overweight females" indicated that a Coleus forskohlii extract promotes favorable changes in body composition.

The 12-week randomized, double-blind, placebo-controlled study of 23 overweight women revealed that individuals receiving coleus forskohlii extract showed decreases in body mass and reported less fatigue and hunger. Additionally, no clinically significant interactions were seen in metabolic markers, blood lipids, muscle and liver enzymes, electrolytes, red cells, white cells, hormones (insulin, TSH, T3, T4), heart rate or blood pressure.

HWy Lipitrex?

The direct and indirect costs of obesity in the United States alone stands at more than $117 billion dollars annually. Direct costs refer to preventive and treatment services related to individuals whom are either overweight or obese. Indirect costs refer to the value of wages lost by weight-caused illness or disability.

What's more, obesity continues to be a key contributor to diseases such as type 2 diabetes, coronary heart disease, and hypertension. Realizing the impact of weight gain on health care costs, there is no wonder why individual's spend additional billions of dollars on ineffective products that do not support one's overall health and weight loss goals. The truth? Obesity costs you thousands in health care costs and wages lost at your job.

Lipitrex has been developed to end the weight loss hype, and to guarantee safe and effective weight loss with time-tested, proven ingredients.

Maybe your goal is to lose a few pounds, or perhaps it is to make dramatic and noticeable changes to your body's image, Lipitrex is a universal 4-in-1 product that can help. It has specifically developed to renew confidence lost by unintentional weight gain. Years of research have gone into Lipitrex's unique formula. In fact, studies have confirmed that the ingredients found in Lipitrex are capable of curbing appetite and promoting significant reductions of stubborn, hard to lose body fat.

Lipitrex has been designed to help you shed pounds the safe, natural way. Progressive Health understands the misconception in the "so-called" weight loss industry and has finally developed a product backed by science, that can help you actually do it. When taken along with a sensible diet and exercise plan Lipitrex is guaranteed to work! Now, you have no excuse and truly have nothing to lose - except maybe those excess pounds!

If you want to shed pounds the safe natural way; Lipitrex can help you do it, along with a sensible diet and exercise plan. It's guaranteed to work!

9/10 customers are satisfied with their purchase from SiSi Health Inc
(based on returns, testimonials, complaints and feedback!)

Magnesium- Magnesium is increasingly studied in relation to obesity and insulin resistance. In fact a recent study showed that deficiency of magnesium is related to insulin resistance as early as childhood and suggested supplementation as an important tool in reducing diabetes in obese children (12). As well, low levels of magnesium prevalent in overweight and obese individuals may be an independent risk factor for cardiovascular disease (13, 14).

Chromium- This required mineral is lacking in many diets and is vital to glucose metabolism as it is a cofactor for glucose tolerance factor. Chromium supplementation has been associated with an increase in lean body mass, a decrease in percentage body fat, and an increase in the basal metabolic rate (8-10). The results of a randomized double blind placebo controlled study of chromium supplementation suggest a relatively small reduction in body weight when compared with placebo during an intervention period of 6–14 weeks in patients with an average BMI of 28–33 (11). The meta-analysis of trials reported an absence of adverse effects.

Green Tea Extract- Green tea has recently been recognized for its ability to increase the metabolism of fat and decrease weight. Green tea is thermogenic in nature; increasing the oxidation of fat molecules in the body. It may prove helpful in persons suffering from obesity and are trying to lose weight.

Coleus Forskohlii- Progressive Health's recently updated Lipitrex formulation includes the Indian plant, Coleus Forskohlii. Coleus forskohlii roots, the only known plant source of forskolin, is a natural compound that has been shown to increase lean body mass and helps optimize body composition through cAMP activation. Raised intracellular cAMP levels have shown to decrease fat deposition and promote other significant physiological and biochemical effects, including:

• Increased insulin secretion
• Increased thyroid function
• Inhibition of mast cell degranulation and histamine release
• Increased force of contraction of heart muscle
• Relaxation of the arteries and other smooth muscles
• Inhibition of platelet activation

However, the greatest benefit witnesses by increases of intracellular cAMP by means of coleus forskolin supplementation still lies within Fat Loss. A study published in the December 2005 Journal of the International Society of Sports Nutrition entitled "Effects of Coleus forskohlii extract supplementation on body composition and markers of health in sedentary overweight females" indicated that a Coleus forskohlii extract promotes favorable changes in body composition.

The 12-week randomized, double-blind, placebo-controlled study of 23 overweight women revealed that individuals receiving coleus forskohlii extract showed decreases in body mass and reported less fatigue and hunger. Additionally, no clinically significant interactions were seen in metabolic markers, blood lipids, muscle and liver enzymes, electrolytes, red cells, white cells, hormones (insulin, TSH, T3, T4), heart rate or blood pressure.

Pinnothin- Derived from the seeds of the Korean Pine Nut tree Pinus koraenisis, this product (which just became widely available in 2005) contains pinolenic acid which helps suppress appetite by stimulating the appetite controlling hormone cholecystokinin (7).

CLA- A clinical study recently concluded, “this study shows that CLA supplementation for 24 mo in healthy, overweight adults was well tolerated. It confirms also that CLA decreases BFM in overweight humans, and may help maintain initial reductions in BFM and weight in the long term (17)”. As well, CLA can reduce all parameters of appetite - hunger, satiety and fullness (18).

Citrus Aurantium Extract- Bitter orange is the common name for this medicinal plant which has an impressive body of research building for its use in weight reduction. A recent study demonstrated that administration of an extract of this plant results in increased thermic response to meals in women and does not cause increases in blood pressure or heart rate (15). A review of clinical studies concluded that citrus aurantium products “may be the best thermogenic substitute for ephedra”, causing an increased metabolic rate (16).

Guarana Extract- This supplement is derived from the seeds of Paullinia cupana. An herbal preparation from South America containing guarana extract demonstrated the ability to significantly delayed gastric emptying, reduced the time to perceived gastric fullness and induced significant weight loss over 45 days in a double-blind placebo-controlled parallel trial (19). Another randomized double blind trial examining the effect of a combination of Ma Huang and Guarana showed significant short term fat and weight loss (20).

Caffeine- Caffeine has long been used for weight loss due to its demonstrable thermogenic effects. A study published this year concluded that high caffeine intake was associated with weight loss through thermogenesis and fat oxidation and with suppressed leptin in women (21). Another randomized double-blind placebo-controlled clinical trial of a product containing ephedrine and caffeine showed that subjects taking the treatment experienced greater weight loss, without an increase in blood pressure, pulse, or the rate of adverse events, and in the absence of any lifestyle treatment to change dietary or exercise behavior (22).